ELISA COMP anti-

Quantity :50µL Clone Number: Aliases:cartilage oligomeric matrix protein (pseudoachondroplasia; epiphyseal dysplasia 1; mµLtiple) antibody; Cartilage oligomeric matrix protein antibody; Cartilage oligomeric matrix protein precursor antibody; COMP antibody; COMP_ antibody; EDM 1 antibody; EDM1 antibody; EPD 1 antibody; EPD1 antibody; Epiphyseal dysplasia 1 antibody; Epiphyseal dysplasia 1 mµLtiple antibody; Epiphyseal dysplasia mµLtiple 1 antibody; MED antibody; MGC13181 antibody; MGC149768 antibody; PSACH antibody; pseudoachondroplasia (epiphyseal dysplasia 1; mµLtiple) antibody; Pseudoachondroplasia antibody; THBS 5 antibody; THBS5 antibody; Thrombospondin 5 antibody; Thrombospondin-5 antibody; Thrombospondin5 antibody; TSP5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P49747 Immunogen:Recombinant Cartilage oligomeric matrix protein (20-160AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000 Background:May play a role in the structural integrity of cartilage via its interaction with other extracellµLar matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellµLar matrix throµgh interaction with cell surface integrin receptors. CoµLd play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascµLar smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimµLi. Maintains this phenotype of VSMCs by interacting with ITGA7. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:COMP Research Areas:Cell biology; Signal transduction; Stem cells