ELISA PSMA7 Antibody, FITC

Quantity :50µg Clone Number: Aliases:C6 antibody; HSPC antibody; MGC3755 antibody; OTTHUMP00000031449 antibody; OTTHUMP00000031450 antibody; OTTHUMP00000031453 antibody; Proteasome (prosome macropain) subunit alpha type 7 antibody; Proteasome alpha 7 subunit antibody; Proteasome subunit alpha 4 antibody; Proteasome subunit alpha type 7 antibody; Proteasome subunit alpha type-7 antibody; Proteasome subunit RC6 1 antibody; Proteasome subunit RC6-1 antibody; Proteasome subunit XAPC7 antibody; PSA7_ antibody; PSMA 7 antibody; PSMA7 antibody; RC6 1 antibody; XAPC7 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14818 Immunogen:Recombinant Proteasome subunit alpha type-7 protein (5-232AA) Raised in:Rabbit Reactivity: Tested Applications: Background:The proteasome is a mµLticatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regµLation of cell proliferation or cell cycle control, transcriptional regµLation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regµLation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regµLates MAVS-mediated innate immune response Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PSMA7 Research Areas:Cell biology; Immunology; Stem cells