ELISA PRMT5 anti-

Quantity :50µL Clone Number: Aliases:72 kDa ICln binding protein antibody; 72 kDa ICln-binding protein antibody; ANM5_ antibody; Histone synthetic lethal 7; S. cerevisiae; homolog of antibody; Histone-arginine N-methyltransferase PRMT5 antibody; HMT1 hnRNP methyltransferase like 5 antibody; HOMOLOG OF; SKB1 antibody; HRMT1L5 antibody; IBP72 antibody; Jak-binding protein 1 antibody; JBP 1 antibody; JBP1 antibody; PRMT 5 antibody; PRMT5 antibody; Protein arginine methyltransferase 5 antibody; Protein arginine N methyltransferase 5 antibody; Protein arginine N methyltransferase 5 N terminally processed antibody; Protein arginine N-methyltransferase 5 antibody; S. POMBE antibody; S. POMBE HOMOLOG OF; SKB1 antibody; SHK1 KINASE BINDING PROTEIN 1 antibody; Shk1 kinase binding protein 1 homolog antibody; Shk1 kinase-binding protein 1 homolog antibody; Shk1 kinase/binding protein 1; S. pombe; homolog of antibody; SKB 1 antibody; SKB1 antibody; SKB1 homolog antibody; SKB1: SKB1 homolog (S. pombe) antibody; SKB1Hs antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14744 Immunogen:Synthetic peptide of PRMT5 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50 Background:Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regµLates cyclin E1 promoter activity and cellµLar proliferation. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRMT5 Research Areas:Epigenetics and Nuclear Signaling