ELISA DHRS2 anti-

Quantity :50µL Clone Number: Aliases:DHRS2 antibody; SDR25C1 antibody; Dehydrogenase/reductase SDR family member 2 antibody; mitochondrial antibody; EC 1.1.1.- antibody; Dicarbonyl reductase HEP27 antibody; Protein D antibody; Short chain dehydrogenase/reductase family 25C member 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13268 Immunogen:Recombinant Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sµgars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resµLting in the accumµLation of MDM2 and CDKN1A/p21. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DHRS2 Research Areas:Cancer; Metabolism; Signal transduction