ELISA PRKCQ (Ab-676) anti-

Quantity :100µL Clone Number: Aliases:KPCT_ antibody; MGC126514 antibody; MGC141919 antibody; nPKC theta antibody; nPKC-theta antibody; nPKCtheta antibody; OTTHUMP00000043364 antibody; OTTHUMP00000043365 antibody; PKC 0 antibody; PKC0 antibody; Prkcq antibody; PRKCT antibody; Protein kinase C theta antibody; Protein kinase C theta type antibody; Protein Kinase Ctheta antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q04759 Immunogen:Peptide sequence around aa. 674~678 (R-L-S-F-A) derived from PKCth. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background:This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellµLar proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Kristof Van Kolen, et al. (2006) FEBS J ; 273: 1843 - 1854. Martin Villalba, et al. (2002) J. Cell Biol ; 157: 253. Jie Zhang, et al. (2004) J. Biol. Chem ; 279: 22118 - 22123. Castro AF, et al. (1998) Am J Physiol Cell Physiol; 275: C113 - C119. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRKCQ Research Areas:Cancer;Metabolism;Signal transduction