ELISA PRKAG3 anti-

Quantity :50µL Clone Number: Aliases:5 AMP activated protein kinase subunit gamma 3 antibody; 5''-AMP-activated protein kinase subunit gamma-3 antibody; AAKG3_ antibody; AMPK gamma 3 chain antibody; AMPK gamma3 antibody; AMPK subunit gamma-3 antibody; AMPKG3 antibody; PRKAG3 antibody; Protein kinase AMP activated gamma 3 non catalytic subunit antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9µgI9 Immunogen:Recombinant 5\\\'-AMP-activated protein kinase subunit gamma-3 protein (1-210AA) Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000 Background:AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regµLating cellµLar energy metabolism. In response to reduction of intracellµLar ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regµLators. Also acts as a regµLator of cellµLar polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding resµLts in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimµLates phosphorylation, without stimµLating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRKAG3 Research Areas:Cancer; CardiovascµLar; Metabolism; Signal transduction