ELISA PRKAA1 (Ab-174|172) anti-

Quantity :100µL Clone Number: Aliases:5 AMP activated protein kinase alpha 1catalytic subunit antibody; 5 AMP activated protein kinase catalytic alpha 1 chain antibody; 5' AMP activated protein kinase catalytic subunit alpha 1 antibody; 5'-AMP-activated protein kinase catalytic subunit alpha-1 antibody; AAPK1 antibody; AAPK1_ antibody; ACACA kinase antibody; acetyl CoA carboxylase kinase antibody; AI194361 antibody; AI450832 antibody; AL024255 antibody; AMP -activate kinase alpha 1 subunit antibody; AMP-activate kinase alpha 1 subunit antibody; AMP-activated protein kinase, catalytic, alpha -1 antibody; AMPK 1 antibody; AMPK alpha 1 antibody; AMPK alpha 1 chain antibody; AMPK antibody; AMPK subunit alpha 1 antibody; AMPK subunit alpha-1 antibody; AMPK1 antibody; AMPKa1 antibody; AMPKalpha1 antibody; C130083N04Rik antibody; cb116 antibody; EC 2.7.11.1 antibody; HMG CoA reductase kinase antibody; HMGCR kinase antibody; hormone sensitive lipase kinase antibody; Hydroxymethylglutaryl CoA reductase kinase antibody; im:7154392 antibody; kinase AMPK alpha1 antibody; MGC33776 antibody; MGC57364 antibody; OTTHUMP00000161795 antibody; OTTHUMP00000161796 antibody; PRKAA 1 antibody; PRKAA1 antibody; Protein kinase AMP activated alpha 1 catalytic subunit antibody; SNF1-like protein AMPK antibody; SNF1A antibody; Tau protein kinase PRKAA1 antibody; wu:fa94c10 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13131 Immunogen:Peptide sequence around aa. 172~176/170~174 (L-R-T-S-C) derived from AMPKa1/AMPKa2. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background:Responsible for the regµLation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regµLates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellµLar ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. Hurley RL, et al. (2005) J Biol Chem. Aµg 12; 280(32): 29060-29066 Woods A, et al. (2003) Curr Biol. Nov 11; 13(22): 2004-2008 Nielsen JN, et al. (2003) J Appl Physiol. Feb; 94(2): 631-641 Da Silva Xavier G, et al. (2000) Proc Natl Acad Sci U S A. Apr 11; 97(8): 4023-4028. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRKAA1 Research Areas:Neuroscience?Cancer?CardiovascµLar;Metabolism;Signal transduction