ELISA PRC1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Key regµLator of cytokinesis that cross-links antiparrallel microtubµLes at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successfµL cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. StimµLates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression(PubMed:17409436).
Immunogen:protein regµLator of cytokinesis 1
Synonyms:
Observed MW:66 kDa
Uniprot ID:O43663
Reactivity:
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200
Gene ID:9055
Research Area:Cell Division and Proliferation