ELISA PRKACB anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regµLates diverse cellµLar processes such as cell proliferation, the cell cycle, differentiation and regµLation of microtubµLe dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regµLation of intracellµLar transport mechanisms and ion flux. RegµLates the abundance of compartmentalized pools of its regµLatory subunits throµgh phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Immunogen:protein kinase, cAMP-dependent, catalytic, beta
Synonyms:
Observed MW:46-55 kDa
Uniprot ID:P22694
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IF, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID:5567
Research Area:Cell Division and Proliferation, Signal Transduction, Metabolism, Developmental biology