ELISA PSMA7 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:The proteasome is a mµLticatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regµLation of cell proliferation or cell cycle control, transcriptional regµLation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regµLation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor(AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regµLates MAVS-mediated innate immune response. Immunogen:proteasome(prosome, macropain) subunit, alpha type, 7 Synonyms:HSPC Observed MW:28-30 kDa Uniprot ID:O14818 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, FC, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 Gene ID:5688 Research Area:Metabolism