ELISA PTBP1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Plays a role in pre-mRNA splicing and in the regµLation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modµLate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10(PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site(IRES) and stimµLates the IRES-mediated translation(PubMed:21518806). Immunogen:polypyrimidine tract binding protein 1 Synonyms:PTB Observed MW:59.6 kDa Uniprot ID:P26599 Reactivity:, Mouse Tested Application:ELISA, WB, IF Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200 Gene ID:5725 Research Area:Epigenetics, Metabolism